Pittsburgh Pirates pitcher Jeff Karstens throws against the Cincinnati Reds in the first inning during a baseball game, Sunday, Oct. 4, 2009, in Cincinnati. (AP Photo/David Kohl)

Pittsburgh Pirates pitcher Jeff Karstens throws in the first inning against the Los Angeles Dodgers in a baseball game in Pittsburgh Friday, Sept. 25, 2009.(AP Photo/Gene J. Puskar)

Washington Nationals' Ryan Zimmerman, left, trots down the third baseline past Pittsburgh Pirates pitcher Jeff Karstens (27) after hitting a two-run home run in the seventh inning of a baseball game at Pittsburgh Monday, Aug. 3, 2009. (AP Photo/Gene ...

Pittsburgh Pirates pitcher Jeff Karstens throws in the first inning against the Houston Astros in a baseball game in Pittsburgh Saturday, May 30, 2009. (AP Photo/Gene J. Puskar)